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InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 μl or 10 mg/924 μl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.
Used in affinity chromatography, protein chromatography and gel filtration chromatography. Sephadex™ G-25 is a gel filtration medium that has been used to study the acceleration of diabetic wound healing and the treatment of epithelial damage.
Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC50 = 665 nM; using CHO transfectants).
A cell-permeable, restricted form of CCG-1423 with enhanced potency (IC50 = 4.2 μM vs 16.6 μM for PC-3 cell migration), but reduced off-target toxicity.
The PI 3-Kγ Inhibitor II, also referenced under CAS 648449-76-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.